Ph.D in Chemistry, National Chemical Laboratory, Pune.
Areas of Interests/Specialization
Biomimetic chemistry, Protein-Protein interactions and protein-DNA interactions, Design and synthesis of peptide mimetics, nucleic acid mimics and proteomimetics, Inhibitors of macromolecular interactions and drug therapeutics, Foldamer chemistry, Polymer based drug delivery.
Assistant Professor, School of Chemical Sciences, Central University of Gujarat, Gandhinagar (Jan 2017-present) Ad hoc faculty, NIT Calicut, Kerala (July 2016-Jan 2017) Marie Curie postdoctoral fellow (Institut Européen de Chimie et Biologie, CNRS, France) - May 2013-April 2015 Post-Doctoral Research Associate (School of Chemistry, University of Leeds, The Astbury Centre for structural molecular Biology) -June 2010- Oct 2012 NIH Post-Doctoral Fellow(Department of Chemistry and Biochemistry, University of California - Los Angeles, USA). March 2009 -April 2010.
Awards & Honours
Marie-Curie Fellowship by European Research Council 2012 ERC post-doctoral fellowship 2010 NIH Post-Doctoral Fellowship 2009 Eli Lilli Asia Outstanding thesis award 2009 JRF & SRF of Council of Scientific and Industrial Research, Govt. of India 2003-2008 Among top 20% in the CSIR-NET exam, 2002 (selected to appear for Shyama Prasad Mukherjee Fellowship) First Rank in M. Sc. Chemistry (General Chemistry with Organic, Inorganic, Physical and Analytical), Mahatma Gandhi University, Kerala, India. Year 2002 Among top ten in B.Sc. Chemistry Examination of Mahatma Gandhi University, Kerala, India, Year 2000. Received fellowship from University College topper in B.Sc. Chemistry Examination of Mahatma Gandhi University, Kerala, India, Year 2000. (Cash prize with memento from St. Joseph’s college Moolamattom, Kerala) Ist class with distinction in 10+2 CBSE examination, 1997 Ist class with distinction in 10th CBSE examination, 1995 Jawahar Navodaya Vidyalaya fellowship 1991-1997.
Best Peer Reviewed Publications
Prabhakaran, P.; Kale, S. S.; Puranik, V. G.; Rajamohanan, P. R.; Chetina, O.; Howard, J. A. K.; Hofmann, H.-J.; Sanjayan, G. J. "Sequnce-Specific Unusual (1→2)-Type Helical Turns in α/β-Hybrid Peptides" J. Am. Chem. Soc., 2008, 130, 17743-17754. Prabhakaran, P.; Puranik, V. G.; Chandran, J. N.; Rajamohanan, P. R.; Hofmann, H.- J.; Sanjayan, G. J. "Novel Foldamer Architecture from Cofacial Aromatic Building Blocks" Chem. Commun., 2009, 3446-3448. Prabhakaran, P.; Priya.; S. G.; Sanjayan, G. J. "Foldamers: They're Not Just for Biomedical Applications Anymore" Angew. Chem. Int. Ed. (Highlights), 2012, 51, 4006-4008. Matsumoto, N. M.; Prabhakaran, P.; Rome L. H.; Maynard H. D. "Smart Vaults: Thermally-Responsive Protein Nanocapsules". ACS Nano, 7, 867-874, 2013.. Ziach, K.; Chollet, C.; Parissi, V.; Prabhakaran, P.; Marchivie, M.; Bose, P. P.; K. L. Reddy, Godde, F.; Chaignepain, S.; Schmitter, J.-M.; Pourquier, P.; Huc. I. "Single helically folded aromatic oligoamides that mimic the charge surface of double-stranded B-DNA" Nature chemistry 2018, 10, 511-518.
Reccent Peer Reviewed Journals/Books
Ziach, K.; Chollet, C.; Parissi, V.; Prabhakaran, P.; Marchivie, M.; Bose, P. P.; K. L. Reddy, Godde, F.; Chaignepain, S.; Schmitter, J.-M.; Pourquier, P.; Huc. I. “Single helically folded aromatic oligoamides that mimic the charge surface of double-stranded B-DNA” Nature chemistry 2018, 10, 511-518 . Reddy, J. P.; Prabhakaran, P.; and J. W. Steed. “Polymorphism of (Z)-3-Bromopropenoic acid: A high and low Z pair”. Cryst. Growth Des. 2016, 16, 4021-4025. Burslem, G. M.; Kyle, H. F.; Prabhakaran, P.; Breeze, A.; Edwards, T. A.; Warriner, S. L.; Nelson, A.; Wilson, A. J. “Synthesis of Highly Functionalized Oligobenzamide Proteomimetic Foldamers by Late Stage Introduction of Sensitive Groups”.Org. Biomol. Chem., 2016, 14, 3782–3786.
Dr Krishna K Damodharan Department of Chemistry, University of Iceland
. Prof Ivan Huc
Patents (If any)