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Dr Panchami Prabhakaran

Assistant Professor

School of Chemical Sciences

Qualifications


  • Ph.D in Chemistry, National Chemical Laboratory, Pune.

Areas of Interest/Specialization


  • Biomimetic chemistry, Protein-Protein interactions and protein-DNA interactions, Design and synthesis of peptide mimetics, nucleic acid mimics and proteomimetics, Inhibitors of macromolecular interactions and drug therapeutics, Foldamer chemistry, Polymer based drug delivery.

Experience


  • Assistant Professor, School of Chemical Sciences, Central University of Gujarat, Gandhinagar (Jan 2017-present)
  • Ad hoc faculty, NIT Calicut, Kerala (July 2016-Jan 2017)
  • Marie Curie postdoctoral fellow (Institut Européen de Chimie et Biologie, CNRS, France) - May 2013-April 2015
  • Post-Doctoral Research Associate (School of Chemistry, University of Leeds, The Astbury Centre for structural molecular Biology) -June 2010- Oct 2012
  • NIH Post-Doctoral Fellow(Department of Chemistry and Biochemistry, University of California - Los Angeles, USA). March 2009 -April 2010.

Awards & Honours


  • Marie-Curie Fellowship by European Research Council 2012
  • ERC post-doctoral fellowship 2010
  • NIH Post-Doctoral Fellowship 2009
  • Eli Lilli Asia Outstanding thesis award 2009
  • JRF & SRF of Council of Scientific and Industrial Research, Govt. of India 2003-2008
  • Among top 20% in the CSIR-NET exam, 2002 (selected to appear for Shyama Prasad Mukherjee Fellowship)
  • First Rank in M. Sc. Chemistry (General Chemistry with Organic, Inorganic, Physical and Analytical), Mahatma Gandhi University, Kerala, India. Year 2002
  • Among top ten in B.Sc. Chemistry Examination of Mahatma Gandhi University, Kerala, India, Year 2000. Received fellowship from University
  • College topper in B.Sc. Chemistry Examination of Mahatma Gandhi University, Kerala, India, Year 2000. (Cash prize with memento from St. Joseph's college Moolamattom, Kerala)
  • Ist class with distinction in 10+2 CBSE examination, 1997
  • Ist class with distinction in 10th CBSE examination, 1995
  • Jawahar Navodaya Vidyalaya fellowship 1991-1997.

Best Peer Reviewed Publications


  • Prabhakaran, P.; Kale, S. S.; Puranik, V. G.; Rajamohanan, P. R.; Chetina, O.; Howard, J. A. K.; Hofmann, H.-J.; Sanjayan, G. J. "Sequnce-Specific Unusual (1?2)-Type Helical Turns in a/β-Hybrid Peptides" J. Am. Chem. Soc., 2008, 130, 17743-17754.
  • Prabhakaran, P.; Puranik, V. G.; Chandran, J. N.; Rajamohanan, P. R.; Hofmann, H.- J.; Sanjayan, G. J. "Novel Foldamer Architecture from Cofacial Aromatic Building Blocks" Chem. Commun., 2009, 3446-3448.
  • Prabhakaran, P.; Priya.; S. G.; Sanjayan, G. J. "Foldamers: They're Not Just for Biomedical Applications Anymore" Angew. Chem. Int. Ed. (Highlights), 2012, 51, 4006-4008.
  • Matsumoto, N. M.; Prabhakaran, P.; Rome L. H.; Maynard H. D. "Smart Vaults: Thermally-Responsive Protein Nanocapsules". ACS Nano, 7, 867-874, 2013..
  • Ziach, K.; Chollet, C.; Parissi, V.; Prabhakaran, P.; Marchivie, M.; Bose, P. P.; K. L. Reddy, Godde, F.; Chaignepain, S.; Schmitter, J.-M.; Pourquier, P.; Huc. I."Single helically folded aromatic oligoamides that mimic the charge surface of double-stranded B-DNA" Nature chemistry 2018, 10, 511-518.

Recent Peer Reviewed Journals/Books


  • Ziach, K.; Chollet, C.; Parissi, V.; Prabhakaran, P.; Marchivie, M.; Bose, P. P.; K. L. Reddy, Godde, F.; Chaignepain, S.; Schmitter, J.-M.; Pourquier, P.; Huc. I. "Single helically folded aromatic oligoamides that mimic the charge surface of double-stranded B-DNA" Nature chemistry 2018, 10, 511-518 .
  • Reddy, J. P.; Prabhakaran, P.; and J. W. Steed. "Polymorphism of (Z)-3-Bromopropenoic acid: A high and low Z? pair". Cryst. Growth Des. 2016, 16, 4021-4025.
  • Burslem, G. M.; Kyle, H. F.; Prabhakaran, P.; Breeze, A.; Edwards, T. A.; Warriner, S. L.; Nelson, A.; Wilson, A. J."Synthesis of Highly Functionalized Oligobenzamide Proteomimetic Foldamers by Late Stage Introduction of Sensitive Groups".Org. Biomol. Chem., 2016, 14, 3782-3786.

International Collaboration/Consultancy


Patents (If any)


  • Not Available.